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Prevention of Nosocomial Infections and Cost-Effectiveness Refined (P-NICER)

Principal Investigator

Patricia Stone, PhD, RN, MPH
Professor of Nursing
Columbia University School of Nursing

Project Summary

Funder: National Institute of Nursing Research, National Institutes of Health
Grant: R01 NR010107
Dates: August 1, 2007 through May 31, 2013
Funding: $3,498,643

Dr. Patricia Stone and her research team were awarded a 3-year competitive renewal for P-NICE, entitled a "€Prevention of Nosocomial Infections and Cost Effectiveness Refined"€ (P-NICER). This $2.1 million award extended their work to qualitatively and quantitatively examine infection prevention in hospitals across the nation, and study variations in state policies regulating mandatory reporting of infection control processes and health care associated infection rates.  The specific aims of this study were to:

  • Describe the level of infection control staffing and intensity of infection prevention and control interventions currently in place in intensive care units (ICU) across the nation;
  • Determine associations between current infection control staffing and intensity of infection prevention and control interventions, and probability healthcare-associated infections and short term survival in elderly ICU patients;
  • Estimate the long term outcomes attributable to healthcare-associated infections in elderly patients; and
  • Determine the cost-effectiveness of effective infection control staffing and infection prevention and control interventions in ICU.


For a full summary of this work including a complete list of publications and presentations, please visit the P-NICE Study website.